12/3/2009 2:00:00 PM

Proteon Therapeutics Named 2010 Technology Pioneer by the World Economic Forum

Proteon

Therapeutics, Inc. has been selected as a 2010

Technology Pioneer by the World

Economic Forum, a Geneva, Switzerland-based independent organization

committed to improving the state of the world. The award will be

presented at the World Economic Forum’s annual meeting in Davos,

Switzerland.

According to the World Economic Forum, the Technology Pioneers represent

the most innovative start-ups from around the globe that will have a

critical impact on the future of business and society. To be selected as

a Technology Pioneer, a company must be involved in the development of a

life-changing technology innovation and have the potential for long-term

impact on business and society. In addition, it must demonstrate

visionary leadership and show all the signs of a long-standing and

sustainable market leader.

Proteon’s designation as a Technology Pioneer is based on its

development of a recombinant human protein, PRT-201, which has been

shown in non-clinical models to rapidly and persistently dilate

localized segments of blood vessels without leaving a permanent implant

behind. If successful in human clinical trials, PRT-201 has the

potential to improve care and quality of life for patients with chronic

kidney and vascular disease. No other currently available drugs or drug

candidates can persistently dilate arteries and veins, and there are

currently no approved drug therapies to improve outcomes of vascular

access surgery. PRT-201 also could reduce healthcare costs for this

patient population by minimizing the need for corrective surgical

procedures and hospitalizations.

Proteon was nominated for the award by one of its largest investors, TVM

Capital, a global venture and growth capital firm headquartered in

Munich, Germany and an investor in Proteon since its Series A financing.

“Proteon exemplifies the type of innovative company that TVM Capital

seeks in its pursuit of promising investment opportunities that have the

potential for global impact,” said Dr. Hubert Birner, General Partner of

TVM Capital and Proteon board member. “We identified Proteon’s unique

breakthrough technology back in 2006 and are proud to have sponsored

Proteon’s application to this year’s World Economic Forum Technology

Pioneers program.”

“The entire Proteon team is honored to be recognized by the World

Economic Forum, alongside a select group of impressive companies

throughout the world, as a 2010 Technology Pioneer,” said Timothy P.

Noyes, President and CEO of Proteon. “This award is the culmination of

years of dedication by our employees and investors, resulting in the

initiation of two Phase 1/2 human clinical trials for our lead product,

PRT-201, the closure of a $50 million Series B financing and a landmark

agreement with Novartis

in 2009.”

In addition to TVM Capital, Proteon’s venture investors include MPM

Bio IV NVS Strategic Fund, L.P., Skyline

Ventures, Prism

VentureWorks, Intersouth

Partners, Bessemer

Venture Partners, Devon

Park Bioventures and the Vectis Healthcare & Life Sciences Fund.

About PRT-201

PRT-201 is a recombinant human elastase that is being studied for its

ability to improve arteriovenous fistula (AVF) surgery outcomes in

patients requiring chronic hemodialysis. PRT-201 has been shown to cause

dilation of segments of arteries and veins following topical

intraoperative application in preclinical models. Vessel dilation and

increased blood flow through the fistula may decrease AVF maturation

failure rates. Improved maturation rates may lead to fewer corrective

surgical procedures, fewer hospitalizations, lower costs and less

suffering for dialysis patients. PRT-201 is also being studied for its

ability to prolong the patency of arteriovenous grafts (AVGs). The

development program to investigate PRT-201 for improving vascular access

has been designated a fast track program by the FDA. PRT-201 has also

received orphan drug designation from FDA for the prevention of AVF

maturation failure and AVG failure in patients with end-stage renal

disease who are on or preparing for hemodialysis.

About Proteon Therapeutics

Proteon Therapeutics, Inc. is a privately held biopharmaceutical company

developing novel, first-in-class pharmaceuticals to address the critical

medical needs of patients with kidney and vascular diseases. The company

is headquartered in Waltham, Mass., and has research facilities in

Kansas City, Mo. For additional information, please visit www.proteontherapeutics.com.

Proteon Therapeutics

Timothy Noyes, 781-890-0102

President/CEO

tnoyes@proteontherapeutics.com

or

PRESS

CONTACT:

Global Prairie

Elizabeth Carttar, 816-994-9824

elizabeth.carttar@global-prairie.com

Tags:
Health, Pharmaceutical, Biotechnology, Clinical Trials