13/07/2010 21:01:00

Vertex Pharmaceuticals Appoints Wayne J. Riley, M.D., to its Board of Directors

Vertex

Pharmaceuticals Incorporated (Nasdaq: VRTX) today announced that

Wayne J. Riley, M.D., M.B.A., joined its board of directors as an

independent director. The addition of Dr. Riley brings the number of

Vertex board members to 10. Dr. Riley was appointed to the class of

directors whose term expires in 2011 and who are subject to re-election

by the company’s shareholders in May 2011.

“Throughout his career, Dr. Riley has been a leader in public health

administration and patient care and will provide a unique perspective to

our board as we seek to bring breakthrough medicines to people with

serious diseases,” said Matthew Emmens, Chairman, President and Chief

Executive Officer of Vertex Pharmaceuticals. “In addition, Dr. Riley’s

clinical and operational experience in the public health systems of

major urban centers and at large academic medical institutions will be

invaluable in our efforts to address the needs of people with hepatitis

C and those involved with treatment of this disease.”

Dr. Riley, 51, is currently the President and Chief Executive Officer of

Meharry Medical College in Nashville, Tennessee, the nation’s largest

private, independent academic health center dedicated to educating

minority and other health professionals. In addition, he holds the

academic rank of Professor of Internal Medicine at both Meharry and

Vanderbilt University Schools of Medicine. Throughout his career, Dr.

Riley has held various leadership roles at academic medical institutions

and has broad experience in public health administration, health policy

and patient care. Prior to his role at Meharry Medical College, which

began in January 2007, Dr. Riley served as a corporate officer as Vice

President and Vice Dean for Health Affairs and Governmental Relations at

the Baylor College of Medicine (BCM) from 2004 to 2006 and as Assistant

Dean for Education at BCM from 2000 to 2004. In his senior role at

Baylor, Dr. Riley was one of three physicians on the institution’s

seven-member senior management team. Dr. Riley began his career in

medicine in 1986 and has practiced at Houston’s Ben Taub General

Hospital, Michael. E. DeBakey Veterans Affairs Medical Center, Methodist

Hospital and St. Luke’s Episcopal Hospitals.

Dr. Riley currently serves as a member of the board of directors for

Pinnacle Financial Partners, Inc., where he serves as a member of the

Audit and Corporate Governance and Nominating Committees, and also sits

on the boards of several non-profit and community service organizations,

including the Nashville Chamber of Commerce, Nashville Health Care

Council, the Nashville Symphony Association, the United Way of

Metropolitan Nashville, the American Cancer Society and the Middle

Tennessee Council for the Boy Scouts of America, among others. He also

serves on the Federal Reserve Bank of Atlanta’s Labor, Education and

Healthcare Advisory Council and the Advisory Council for the National

Institute on Minority Health and Health Disparities of the National

Institutes of Health.

Dr. Riley earned a Bachelor of Arts degree from Yale University in New

Haven, Connecticut, a Master of Public Health degree from the Tulane

University School of Public Health and Tropical Medicine in New Orleans,

Louisiana, a Doctor of Medicine degree from the Morehouse School of

Medicine in Atlanta, Georgia and a Master of Business Administration

degree from the Rice University Jesse H. Jones Graduate School of

Business. Dr. Riley is a Regent and Master of the American College of

Physicians, a member of the Society of Medical Administrators, a

Diplomate of both the American Board of Internal Medicine and the

National Board of Medical Examiners, Chair of the Board of the

Association of Minority Heath Professions Schools, and a member of Alpha

Omega Alpha Honor Medical Society.

About Vertex

Vertex Pharmaceuticals Incorporated is a global biotechnology company

committed to the discovery and development of breakthrough small

molecule drugs for serious diseases. The Company's strategy is to

commercialize its products both independently and in collaboration with

major pharmaceutical companies. Vertex's product pipeline is focused on

viral diseases, cystic fibrosis, inflammation, autoimmune diseases,

epilepsy, cancer, and pain.

Vertex's press releases are available at www.vrtx.com.

(VRTX-GEN)

Vertex Pharmaceuticals Incorporated

Investors:

Michael

Partridge, 617-444-6108

or

Matt Osborne, 617-444-6057

or

Media:

Zachry

Barber, 617-444-6470

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